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Khondrion: fully operational since 2012 and located in Nijmegen, The Netherlands, Khondrion primarily focuses on the development of innovative therapies for inherited mitochondrial diseases, including Leigh Disease, MELAS, Leber’s Hereditary Optic Neuropathy and other Respiratory Chain / Oxidative Phosphorylation disorders. The company's focus is on its own product development programmes. Khondrion has extensive experience in mitochondrial medicine, unique quantitative live-cell imaging technologies and in-depth characterised patients-derived cell panels. In this scope, the company developed a portfolio of pre-clinical drug candidates, among them the frontrunner KH176 is currently under clinical evaluation. Khondrion will also offer a possibility of short visits/secondments for the ESRs in order to conduct parts of their research or learn specific methodologies. A high-end course in advanced methodologies for analysis of mitochondrial function with the title “Drug Development for modulators of mitochondrial dysfunction” will be organized by Khondrion with a direct interest in mitochondrial pathophysiology.

 

 

Partner Organizations:

 

 

Oroboros: provides the worldwide leading concept and technology for highresolution respirometry applied to the functional diagnosis of mitochondrial defects by simultaneous monitoring metabolic parameters in small samples of biopsies, cultured cells and isolated mitochondria. Oroboros will also offer a possibility of short visits/secondments for the ESRs in order to conduct parts of their research or learn specific methodologies. A high-end course in advanced methodologies for analysis of mitochondrial function with the title “High-Resolution Respirometry (HRR) and O2k-Fluorometry” will be organized by Oroboros with a direct interest in mitochondrial pathophysiology.

 

 

CMMC - Center for Molecular Medicine Cologne: CMMC is a joint enterprise of the Faculty of Medicine, and the Faculty of Mathematics and Natural Sciences at the University of Cologne. It offers its members a platform to exploit synergies in the exploration of molecular and cellular mechanisms of human diseases and access to funding in competitive funding programs. CMMC manages the scientific exchange but also takes responsibility for the project management of third-party funded projects in the Faculties. CMMC will offer two ESRs short stay visits (max 3 months each) to gather experiences in large network maintenance and funding program management. Students will organize seminars and support scientists in exchanges views and ideas. They will also be introduced in the controlling of third-party funded projects, organization of call for proposals and selection procedures.

 

 

 

German EIT Health GmbH (EIT-Health): EIT-Health is a small sized company with 6 FTE located with office space in Heidelberg and Mannheim. It is the national hub of Europe's largest public-privatepartnership in the detection and validation of innovative academic research results and entrepreneurial capacity in the field of health and health care. More than 150 partners from big-pharma, nutritional and consumer care businesses, IT and med-tech companies, public higher education and research organization form a sustainable partnership under the umbrella of the European Institute for Innovation and Technology. EIT-Health will offer access to international entrepreneurship courses for young life scientists and will offer a one-day workshop on the transfer of results all along the value chain. Additionally two ESRs will be offered short stay visits (max 3 months each) in the Heidelberg offices to learn the business perspective on technology transfer.

 

 

Science Craft: equips life scientists with the skills needed to launch a successful research career. By bridging the training gaps confronting researchers, Science Craft’s workshops enable life scientists to get their research funded, published and cited at the highest level. Our training also enables top-tier graduate schools to gain a distinct advantage in the competition to attract the best international students. All workshops are self-contained but complement each other thus providing researchers with the necessary toolkit required to write research articles and funding proposals as well as navigate the peer review process.